SS-31 (Elamipretide)

SS-31 (Elamipretide)

10 MG
$89.00
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SS-31 (Elamipretide)
  • SS-31 (Elamipretide)
  • SS-31 (Elamipretide)
SS-31 (Elamipretide)

SS-31 (Elamipretide)

$89.00
mg
COA Certified

***Our 2026 Janoshik testing has commenced. New COA’s will be updated shortly

For research purposes only – no human use.

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SS-31 (Elamipretide) 

SS-31 is supplied strictly as a laboratory research material for analytical and scientific use only. Available to qualified researchers, laboratories, and institutions in Perth and across Western Australia, with Australian-based fulfilment.

Intended for in‑vitro research, assay development, method validation, and controlled scientific investigation by appropriately qualified professionals.

Product details

  • Product: SS-31
  • Molecular Formula: D-Arg-dimethylTyr-Lys-Phe-NH₂
  • Strength / size: 10 MG/ 50 MG
  • Category: Research compound / research peptide
  • Form: Lyophilised powder
  • Use: Laboratory research only
  • Supply: Perth & Western Australia (AU shipping)

OTHER KNOWN TITLES: Elamipretide, Bendavia, or MTP-131

SS-31 (Elamipretide) is a synthetic tetrapeptide (composed of four amino acids) with the sequence D-Arg-Dmt-Lys-Phe-NH2.  It belongs to a class of Mitochondria-Targeted Therapeutics (MTTs) known as aromatic-cationic peptides. 

Unique Mechanism

Unlike many other peptides that work on surface receptors, SS-31 was engineered to specifically target the mitochondria—the energy-producing organelles inside cells. This makes it one of the most direct tools for addressing mitochondrial dysfunction.

  •  Target: What makes SS-31 unique is its high affinity for cardiolipin, a phospholipid found in the inner mitochondrial membrane that is essential for maintaining mitochondrial structure and energy production. 

  •  Action: By binding directly to cardiolipin, SS-31 protects the integrity of the mitochondrial membrane and helps optimize cellular energy output. It was specifically engineered to penetrate the cellular outer membrane and selectively accumulate within the mitochondria.

he power of SS-31 lies in its direct targeting of mitochondria, making it one of the few peptides that works inside the cell’s energy center rather than on surface receptors. SS-31 functions as a structural stabilizer and antioxidant within the powerhouse of the cell, correcting the underlying energetic deficits associated with aging and disease.

Key Mitochondrial Actions

  • Cardiolipin Stabilization: SS-31 selectively targets and binds to Cardiolipin (CL), a unique phospholipid found almost exclusively in the inner mitochondrial membrane (IMM). This binding stabilizes the IMM structure, maintaining the optimal organization of the Electron Transport Chain (ETC) supercomplexes for efficient ATP production.

  • ROS Scavenging: It acts as a powerful antioxidant at the source of Reactive Oxygen Species (ROS) generation (the IMM), directly mitigating oxidative stress and preventing Cardiolipin peroxidation.

  • mPTP Inhibition: SS-31 reduces the opening of the Mitochondrial Permeability Transition Pore (mPTP). This pore opening is a critical event leading to mitochondrial membrane potential collapse and apoptosis (cell death) during cellular stress (EX: calcium overload).

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