{"product_id":"kpv-5mg","title":"KPV | 5mg","description":"\u003ch2\u003eKPV | 5mg\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eKPV\u003c\/strong\u003e is supplied strictly as a \u003cstrong\u003elaboratory research material\u003c\/strong\u003e for analytical and scientific use only. Available to qualified researchers, laboratories, and institutions in \u003cstrong\u003ePerth\u003c\/strong\u003e and across \u003cstrong\u003eWestern Australia\u003c\/strong\u003e, with Australian-based fulfilment.\u003c\/p\u003e\n\u003cp\u003eIntended for \u003cstrong\u003ein‑vitro research\u003c\/strong\u003e, assay development, method validation, and controlled scientific investigation by appropriately qualified professionals.\u003c\/p\u003e\n\u003ch3\u003eProduct details\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct:\u003c\/strong\u003e KPV\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula: \u003c\/strong\u003eC\u003csub\u003e16\u003c\/sub\u003eH\u003csub\u003e30\u003c\/sub\u003eN\u003csub\u003e4\u003c\/sub\u003eO\u003csub\u003e4\u003c\/sub\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStrength \/ size:\u003c\/strong\u003e KPV 5 Mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCategory:\u003c\/strong\u003e Research compound \/ research peptide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUse:\u003c\/strong\u003e Laboratory research only\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupply:\u003c\/strong\u003e Perth \u0026amp; Western Australia (AU shipping)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e\u003cstrong\u003eSEQUENCE:\u003c\/strong\u003e\u003cspan\u003e Lys-Pro-Val\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cmeta charset=\"UTF-8\"\u003e \u003cstrong\u003eOTHER KNOWN TITLES:\u003c\/strong\u003e MSH(11-13), ACTH(11-13), alpha-MSH(11-13)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cmeta charset=\"UTF-8\"\u003eKPV is the C-terminal peptide stretch of alpha-melanocyte-stimulating hormone (alpha-MSH). The peptide consists of the last three amino acids of the alpha-MSH hormone. It has been explored for its potential anti-inflammatory properties at the cellular level. Comprising the amino acids L-Lys-L-Pro-L-Val, KPV represents the minimal sequence that may mitigate inflammation in experimental models. However, the precise mechanisms of its action still need to be further studied in order to be more fully understood.\u003cbr\u003e\u003cbr\u003eThis peptide’s various mechanisms may potentially differentiate from that of alpha-MSH, which researchers believe interacts with the melanocortin-1 receptors by theoretically activating the cAMP pathway. Instead, studies suggest a rapid and acute increase in intracellular calcium when KPV is introduced alongside N6-(L-2-phenyl isopropyl) adenosine (PIA), an adenosine agonist that inhibits the cAMP pathway.\u003cbr\u003e\u003cbr\u003eFurther data-gathering investigations using cells transfected with melanocortin-1 receptors have indicated that KPV may, in theory, elevate intracellular calcium levels. This may imply an additional type of interaction with this receptor. This calcium signaling is thought to contribute to the inhibition of the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), a transcription factor involved in inflammatory responses. By potentially inhibiting NF-κB activation, KPV might modulate inflammatory processes within cells.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"BioTech Perth","offers":[{"title":"Default","offer_id":45495226269869,"sku":"BTP-008","price":67.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0741\/3887\/8125\/files\/KPV-5MG.png?v=1766302353","url":"https:\/\/perthbiotech.com\/products\/kpv-5mg","provider":"Perth BioTech - Perth’s trusted source for precision research peptides.","version":"1.0","type":"link"}